Effect of Protein Intake on Lean Body Mass in Functionally ...
The design of the trial has been published previously. 31 The Optimizing Protein Intake in Older Men (OPTIMen) Trial was a randomized, placebocontrolled, doubleblind, parallelgroup trial with a 2 × 2 factorial design (Supplement 1). Institutional review boards at Brigham and Women's Hospital and Boston Medical Center approved the study.